Table 1.

Plasma triglycerides, total and HDL cholesterol, glucose and insulin in Pcsk7^+/+ and Pcsk7^-/- mice.

	Male		Female
	Pcsk7+/+	Pcsk7-/-	Pcsk7+/+	Pcsk7-/-
Triglycerides (mg/dL)	43.2 ± 3.3	45.1 ± 3.6	27.8 ± 3.6	25.1 ± 2.9
Total cholesterol (mg/dL)	112.7 ± 5.1	113.6 ± 5.9	94.4 ± 5.2	95.4 ± 1.6
HDL cholesterol (mg/dL)	99.6 ± 3.9	104.7 ± 5.2	84.6 ± 5.0	89.1 ± 1.7
Glucose (mmol/L)	8.3 ± 0.5	8.1 ± 0.6	7.7 ± 0.4	8.8 ± 0.6
Insulin (ng/mL)	1.5 ± 0.3	1.3 ± 0.2	0.9 ± 0.2	0.8 ± 0.1

Values are means ± S.E.M. Plasma samples were collected after 4 h fasting from 3- to 4-month-old C57BL/6J Pcsk7^+/+ or Pcsk7^-/- mice. Triglycerides were determined using the Wako kit (n = 18–19 mice/group for male and n = 8 mice/group for female). Total and HDL cholesterol measurements were performed on a Roche Cobas Integra 400 plus analyzer (n = 6 mice/group for male and n = 5 mice/group for female). Glucose levels were determined using an automatic glucometer and insulin levels were measured using the Mouse Insulin Ultrasensitive ELISA Kit from Alpco Diagnostics (n = 12–14 mice/group for male and n = 6 mice/group for female). Abbreviation: HDL, High density lipoprotein.