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. 2014 Oct 10;5:5208. doi: 10.1038/ncomms6208

Table 1. Parameters used in the numerical simulations of the model.

Parameter Description Value Source
ρ* Resource conversion coefficient (B, Bp, C, Cp) (1.232, 0.925, 0.916, 1.198) × 109 OD600 data (MCMC)
Inline graphic Specific affinity (B, Bp, C, Cp) (6.305, 8.162, 10.704, 6.627) × 10−10 OD600 data (MCMC)
σ* Segregation rate σb=0.00479, σc=0.01223 qPCR data
γ* Antibiotic killing rate γ=0.1, γp=18 × 10−4 MIC data
α* Antibiotic degradation rate α=10 × 10−8, αp=10 × 10−7 Drug degradation data
ε Rate of point mutation 10 × 10−7  
δ Dilution parameter 0.1% of volume  

MCMC, Markov-chain Monte Carlo; MIC, minimal inhibitory concentration; qPCR, quantitative PCR.