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. Author manuscript; available in PMC: 2014 Oct 24.
Published in final edited form as: Cell Calcium. 2013 Jan 20;53(4):256–263. doi: 10.1016/j.ceca.2012.12.006

Fig. 5.

Fig. 5

The effect of glucocorticoids on glutamate-induced calcium signal in co-cultured neurons and astrocytes. (A) 5 μM glutamate induced typical [Ca2+]c rise cortical neurons. Application of DEX (1 μM, B) or corticosterone (1 μM, C) significantly decreased the amplitude of calcium rise in response to 5 μM glutamate. (D) Differences in the amplitude (fura-2 ratio) of glutamate (5 μM)-induced calcium signal in the presence of DEX (1 μM) and corticosterone (1 μM) (*P < 0.05 and **P < 0.01).