Table 1.
SNP | CHR | Position | Major allele | Frequency of major allele | RSQRa | Effect 1 | OR | SEM | LR chi square | P value of LR | Symbol | Predicted function | Splice distance |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
rs61973742 | 13 | 102083273 | A | 0.9384 | 0.8881 | 1.579 | 4.848 | 0.415 | 23.9755 | 9.76E-07 | NALCN | 5′ Upstream | |
rs1338051 | 13 | 102062341 | G | 0.6595 | 0.9932 | −0.481 | 0.618 | 0.1 | 22.5497 | 2.05E-06 | NALCN | Intronic | 6323 |
rs9518385 | 13 | 102060280 | A | 0.6597 | 0.9947 | −0.48 | 0.618 | 0.1 | 22.5411 | 2.06E-06 | NALCN | Intronic | 8384 |
rs9518384 | 13 | 102059871 | C | 0.6597 | 0.9951 | −0.48 | 0.619 | 0.1 | 22.5246 | 2.08E-06 | NALCN | Intronic | 8355 |
rs1338041b | 13 | 102058862 | A | 0.6597 | 0.9955 | −0.48 | 0.619 | 0.1 | 22.4931 | 2.11E-06 | NALCN | Intronic | 7346 |
rs619152b | 13 | 110939497 | G | 0.6437 | 0.9328 | −0.489 | 0.614 | 0.103 | 22.1724 | 2.49E-06 | COL4A1 | Intronic | 19794 |
rs3916908 | 13 | 102058054 | A | 0.6602 | 0.9949 | −0.477 | 0.621 | 0.1 | 22.1374 | 2.54E-06 | NALCN | Intronic | 6538 |
rs12132318 | 1 | 183797688 | T | 0.9376 | 0.3209 | −1.422 | 0.241 | 0.28 | 22.0992 | 2.59E-06 | RGL1 | Intronic | 19012 |
rs67863238 | 11 | 48267856 | G | 0.9439 | 0.8808 | 1.608 | 4.994 | 0.442 | 21.7354 | 3.13E-06 | OR4X2 | 3′ Downstream | |
rs1249277 | 10 | 28720076 | G | 0.8497 | 0.9894 | −0.574 | 0.563 | 0.118 | 21.5017 | 3.54E-06 | Intergenic | ||
rs1249281 | 10 | 28716177 | G | 0.8505 | 0.9956 | −0.572 | 0.564 | 0.118 | 21.3706 | 3.79E-06 | Intergenic | ||
rs9416795b | 10 | 28709550 | G | 0.8508 | 0.9998 | −0.57 | 0.565 | 0.118 | 21.2877 | 3.95E-06 | Intergenic | ||
rs10930717 | 2 | 176742322 | G | 0.9524 | 0.9092 | −0.896 | 0.408 | 0.177 | 21.1596 | 4.23E-06 | KIAA1715 | 3′ Upstream | |
rs35875350 | 11 | 48230490 | G | 0.9433 | 0.9333 | 1.513 | 4.538 | 0.421 | 20.9828 | 4.63E-06 | OR4B1 | 5′ Upstream |
Quality measure of imputation, from 0 to 1, with values <0.3 suggestive of poorly imputed.
SNP also found in the nonimputed genotype platform.
SNP, single-nucleotide polymorphism; CHR, chromosome; RSQR, r squared (r2); OR, odds ratio; SEM, standard error of the mean; LR, likelihood ratio.