Figure 3.

Vascular dynamics of non-spherical nanoconstructs. (a) Fast moving RBCs confine submicrometre-sized nanoconstructs in proximity of the vessel walls, which favours the recognition of the diseased endothelium [12]. (b) Thin discoidal nanoconstructs drift laterally, across the stream lines, with a higher velocity as compared to spherical, quasi-hemispherical or thick discoidal nanoconstructs [78]. (c) In vitro parallel plate flow chamber experiments confirm that thin discoidal nanoconstructs would deposit and adhere more efficiently than spherical and quasi-hemispherical nanoconstructs, over a wide range of wall shear rates S [79].