Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jun 11;2(6):e12039. doi: 10.14814/phy2.12039

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 3. — Loss of α‐catenin expression decreases N‐cadherin expression. (A) A loss of N‐cadherin protein expression in cortical lysates from male Fischer 344 rats at 20, or 24 months is shown; each lane represents a sample from an individual animal. (B) Densitometric analysis of N‐cadherin expression, normalized to β‐actin; n = 3–7 animals, *indicates a significant difference from 4 months. (C) The age‐dependent loss of N‐cadherin is also seen in the aging nonhuman primate kidney, as shown by western blot of kidney lysates in the bottom panel. (D) The expression of Twist1 is decreased in C2 cells as compared to NT3 controls; similar results were seen in independent experiments.