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. 2014 Sep 23;77(10):2241–2247. doi: 10.1021/np500498j

Figure 2.

Figure 2

PD1 (3) and 22-OH-PD1 (6) limit leukocyte recruitment in vivo. Mice were administered vehicle (saline containing 0.1% EtOH), PD1 (3) (10 ng/mouse), or 22-OH-PD1 (6) (10 ng/mouse) i.p. 10 min prior to zymosan (1 mg/mouse, i.p.). At 4 h peritoneal lavages were collected and cells enumerated using light microscopy and flow cytometry. (A) Representative flow cytometry dot plots. (B) Total leukocyte counts in murine peritoneal lavages. Results for A are representative of n = 4 mice per treatment. Results for B are mean ± SEM; n = 4 mice per treatment. *p < 0.05, **p < 0.01 versus zymosan-treated mice.