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. Author manuscript; available in PMC: 2014 Oct 24.
Published in final edited form as: Anal Biochem. 2010 Nov 25;410(1):141–148. doi: 10.1016/j.ab.2010.11.033

Figure 1.

Figure 1

Illustration of the imunno-nanoparticle-PCR sandwich. RSV antigen (green) is captured and separated using antibody functionalized 1 μm magnetic microparticles (gray). The magnetic bead- antigen complex is then reacted with antibody-DNA functionalized 15 nm AuNPs (red). Hybridized DNA (blue) is released from the AuNPs by heating and quantified via real-time PCR.