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. Author manuscript; available in PMC: 2014 Oct 24.
Published in final edited form as: Chem Res Toxicol. 2009 Mar 16;22(3):433–445. doi: 10.1021/tx8002752

Table 2.

Functional analysis of BH and HNE datasetsa

Biological Function p-valuea
BH HNE
6 h 24 h 6 h 24 h
Amino Acid Metabolism < 10−04 2.03 × 10−04
Carbohydrate Metabolism 5.54 × 10−04
Cell Cycle 5.54 × 10−04 7.24 ×10−04 < 10−04 < 10−04
Cell Death 2.41 × 10−04 < 10−04 < 10−04
Cell Morphology 7.10 × 10−04 < 10−04 < 10−04
Cell Signaling 5.61 × 10−04 < 10−04
Cell-To-Cell Signaling and Interaction < 10−04 < 10−04 < 10−04
Cellular Assembly and Organization 1.61 × 10−04 < 10−04 < 10−04
Cellular Compromise < 10−04
Cellular Development 5.54 × 10−04 < 10−04 < 10−04
Cellular Function and Maintenance 2.84 × 10−04 < 10−04 < 10−04
Cellular Growth and Proliferation < 10−04 < 10−04
Cellular Movement < 10−04 < 10−04
DNA Replication, Recombination, and Repair < 10−04 < 10−04
Free Radical Scavenging 5.54 × 10−04
Gene Expression < 10−04 < 10−04
Lipid Metabolism 5.54 × 10−04
Molecular Transport 5.54 × 10−04 < 10−04
Post-Translational Modification 6.25 × 10−04 < 10−04 < 10−04
Small Molecule Biochemistry 5.54 × 10−04 < 10−04 2.03 × 10−04
Vitamin and Mineral Metabolism < 10−04
a

Ingenuity Pathway Analysis uses a right-tailed Fisher Exact Test to calculate p-values. Significance values for each dataset indicate the probability that the association between the genes and the given molecular and cellular functions are due to random chance.