Table 4.
Select Gene Expression Changes Mediated by BHa
| Gene Symbol |
Description | Fold Change | MGI Gene ID |
||
|---|---|---|---|---|---|
| 6 h | 24 h | ||||
| Interferon- associated Signaling or Regulation |
H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 |
−1.8 | 103070 | |
| H2-Q1 | histocompatibility 2, Q region locus | −4.8 | 95928 | ||
| Immune Response |
Ccl2 | chemokine (C-C motif) ligand 2 | 2.2 | 98259 | |
| Ccl6 | chemokine (C-C motif) ligand 6 | 5.4 | 98263 | ||
| Cd2 | CD2 antigen | 102.4 | 88320 | ||
| Csf2 | colony stimulating factor 2 (granulocyte-macrophage) |
−12.1 | 1339752 | ||
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 1.9 | 1340094 | ||
| Ereg | epiregulin | 13.2 | 107508 | ||
| Fos | FBJ osteosarcoma oncogene | −3.6 | 95574 | ||
| Il1a | interleukin 1 alpha | 6.0 | 96542 | ||
| Il20 | interleukin 20 | 2.4 | 1890473 | ||
| Oxidative Stress Response |
Hmox1 | heme oxygenase (decycling) 1 | 6.0 | 96163 | |
| Cell Structure | Pstpip2 | proline-serine-threonine phosphatase interacting protein 2 |
6.1 | 1335088 | |
| Tuba4 | tubulin, alpha 4 | 1.9 | 1095410 | ||
a
Genes altered ≥1.8-fold (p ≤ 0.01) up or down in LPS stimulated BH-treated cells relative to LPS stimulated cells. Fold changes (FC) represent the average of three independent biological experiments.