Table 4.
Areas with smaller regional GM and WM volumes in nonresponder OCD patients (n=15) than in healthy participants (n=30)
| Region | Brodmann’s area | Talairach coordinate (mm)
|
Voxels in cluster | T-value | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Rt thalamus | 3 | −5 | 0 | 2,486 | 4.87 | |
| Rt caudate | 6 | 0 | 4 | 2,486 | 4.54 | |
| Lt posterior cingulate cortex | 30 | −21 | −59 | 9 | 1,707 | 8.28 |
| Lt posterior cingulate cortex | 30 | −14 | −65 | 10 | 1,707 | 4.79 |
| Rt inferior frontal white matter | 17 | 57 | −13 | 1,178 | 5.90 | |
| Rt inferior frontal white matter | 11 | 53 | −13 | 1,178 | 5.14 | |
| Rt inferior frontal white matter | 13 | 40 | −19 | 1,178 | 4.84 | |
| Lt cingulate bundle | −25 | −60 | 14 | 1,142 | 4.51 | |
Notes: FDR set at 0.05. Results of a voxel-wise SPM analysis.
Abbreviations: FDR, false discovery rate; GM, gray matter; Lt, left; OCD, obsessive-compulsive disorder; Rt, right; SPM, statistical parametric mapping; WM, white matter.