Table 5.
Areas with smaller regional GM and WM volumes in responder OCD patients (n=24) than in healthy participants (n=30)
| Region | Brodmann’s area | Talairach coordinate (mm)
|
Voxels in cluster | T-value | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Lt dorsolateral prefrontal | 8 | −52 | 10 | 40 | 848 | 7.17 |
| Lt dorsolateral prefrontal | 8 | −39 | 21 | 42 | 848 | 6.50 |
| Lt superior frontal white matter | −30 | −11 | 47 | 948 | 6.37 | |
| Lt superior frontal white matter | −36 | −17 | 55 | 948 | 5.26 | |
Notes: FDR set at 0.05. Results of a voxel-wise SPM analysis.
Abbreviations: FDR, false discovery rate; GM, gray matter; Lt, left; OCD, obsessive-compulsive disorder; SPM, statistical parametric mapping; WM, white matter.