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. 2014 Oct 24;9(10):e109531. doi: 10.1371/journal.pone.0109531

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© 2014 Shimizu et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) The number (percentage) of CD4⁺CD25⁺ T cells was higher in SR-A^−/− NOD mice (6 weeks of age) treated with poly(I∶C) (n = 3) than in untreated SR-A^−/− NOD mice (n = 7), suggesting that CD4⁺CD25⁺ T cells mainly comprised pathogenic T cells. mean ± SD. * p value = 0.0167. (B) The number (percentage) of CD4⁺Foxp3⁺ T cells in SR-A^−/− NOD mice (6 weeks of age) treated with poly(I∶C) (n = 3) was similar to that in untreated SR-A^−/− NOD mice (n = 7), mean ± SD. p value = 0.5167.