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. 2014 Oct 24;9(10):e110790. doi: 10.1371/journal.pone.0110790

Table 3. Clinical Characteristics of the study population at admission, by study groups.

Clinical Characteristics Cases: Patients testing positive for C. difficile (N = 212) Patients without C. difficile infection
Patients negative on C. difficile test - Controls type 1 (N = 185) Patients without a C. difficile test - Controls type 2 (N = 159)
Primary Diagnosis, % (n)
Cardiovascular 16.5% (34) 17.8% (33) 18.2% (29)
Infectious 67.0% (142) 58.9% (109) 61.6% (98)
Neoplasm 8.0% (17) 11.4% (21) 8.8% (14)
Orthopedics 3.3% (7) 2.7% (5) 0.6% (1)
Renal 2.8 (6) 2.7% (5) 6.9 (11)
Others 2.8 (6) 6.5% (12) 3.8 (6)
(pv vs. cases) (pv = 0.370) (pv = 0.199)
Co-morbidities, % (n) (pv vs. cases)
History MI 19.8%(42) 27.6%(51) (pv = 0.182) 25.2%(40) (pv = 0.532)
Heart failure 43.3%(94) 40.5%(75) (pv = 0.177) 40.3%(64) (pv = 0.306)
Chronic Pulmonary Disease 8.0%(17) 8.6%(16) (pv = 0.839) 11.3%(18) (pv = 0.850)
Pneumonia 30.2% (17) 30.3% (56) (pv = 1.000) 20.8% (33) (pv = 0.030)
Diabetes 34.4%(73) 37.3%(69) (pv = 1.000) 34.6%(55) (pv = 0.810)
Hypertension 46.2%(98) 48.1%(89) (pv = 0.644) 52.2%(83) (pv = 0.550)
Chronic Renal Failure 13.7%(29) 14.1%(26) (pv = 0.880) 13.2%(21) (pv = 0.424)
Peptic Ulcer Disease 4.7%(10) 4.9%(9) (pv = 1.000) 2.5%(4) (pv = 0.344)
Cancer 19.3%(41) 26.5%(49) (pv = 0.057) 19.5%(31) (pv = 1.000)
Anemia 40.1%(85) 37.8%(70) (pv = 1.000) 28.3%(43) (pv = 0.001)
Charlson Index
Mean±SD 5.0±3.3 5.6±3.9 5.0±3.3
Median 5.0 6.0 5.0
Min-Max (pv vs. cases) 0.0–19.0 0.0–18.0 (pv = 0.114) 0.0–15.0 (pv = 0.520)