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. 2014 Oct 24;9(10):e111146. doi: 10.1371/journal.pone.0111146

Table 2. Frequently mutated kinase genes in the 18 Asian gastric cell lines.

Gain Loss LOH
Kinase Number ofcell lines Kinase Number ofcell lines Kinase Number ofcell lines
CDK13 13 (72%) MAP3K15 8 (44%) GUCY2F 11 (61%)
EGFR 13 RPS6KA6 8 PAK3 11
STK17A 13 PRKX 8 CDKL5 11
PHKG1 12 GUCY2F 8 MYLK3 10
CAMK2B 12 RPS6KA3 8 RPS6KA3 10
STK31 12 MST4 8 RPS6KA6 10
HCK 11 NRK 8 MAP3K15 10
SRC 11 BMX 7 WNK3 10
AURKA 11 TAF1 7 PIM2 9
ADCK5 10 PDK3 7 BTK 9
STK3 10 JAK2 7 CASK 9
SGK2 10 CASK 7 CDK16 9
PAK1 10 CDK16 6 PDK3 9
SRMS 10 ALPK2 6 ARAF 9
EIF2AK1 10 PAK3 6 PRKX 9