Table 2. Frequently mutated kinase genes in the 18 Asian gastric cell lines.
Gain | Loss | LOH | |||
Kinase | Number ofcell lines | Kinase | Number ofcell lines | Kinase | Number ofcell lines |
CDK13 | 13 (72%) | MAP3K15 | 8 (44%) | GUCY2F | 11 (61%) |
EGFR | 13 | RPS6KA6 | 8 | PAK3 | 11 |
STK17A | 13 | PRKX | 8 | CDKL5 | 11 |
PHKG1 | 12 | GUCY2F | 8 | MYLK3 | 10 |
CAMK2B | 12 | RPS6KA3 | 8 | RPS6KA3 | 10 |
STK31 | 12 | MST4 | 8 | RPS6KA6 | 10 |
HCK | 11 | NRK | 8 | MAP3K15 | 10 |
SRC | 11 | BMX | 7 | WNK3 | 10 |
AURKA | 11 | TAF1 | 7 | PIM2 | 9 |
ADCK5 | 10 | PDK3 | 7 | BTK | 9 |
STK3 | 10 | JAK2 | 7 | CASK | 9 |
SGK2 | 10 | CASK | 7 | CDK16 | 9 |
PAK1 | 10 | CDK16 | 6 | PDK3 | 9 |
SRMS | 10 | ALPK2 | 6 | ARAF | 9 |
EIF2AK1 | 10 | PAK3 | 6 | PRKX | 9 |