Table 3. HPLC analysis of LMDP in liposomes after treatment with cell membranes containing γ-secretase.
Sample | peak area (µV/sec) | cleavage efficiency (%) |
LMDP-liposome | 110608±38188 | – |
LMDP-liposome+membrane fraction | 67823±20184 | 36.8±7.0 |
The constitution of LMDP-liposome was EPC/DOPE/CHEMS (4.5∶4.5∶2) containing 3 mol% LMDP.