Table 1.

SHIRPA primary screen score in glut3+/− mice (n = 28) and WT control mice (n = 27).

	WT littermates	glut3+/−	p-value
Viewing jar
Body position	3.30±0.09	3.04±0.04	0.097
Spontaneous activity	1.82±0.14	1.89±0.09	0.595
Respiration rate	2.00±0.00	2.00±0.00	1.000
Tremor	0.67±0.13	0.68±0.10	0.826
Urination	0.07±0.05	0.07±0.05	0.993
Defecation	3.63±0.27	4.11±0.48	0.539
Arena
Transfer arousal	3.41±0.23	3.79±0.17	0.288
Locomotor activity	8.82±0.77	8.50±0.72	0.686
Palpebral closure	0.00±0.00	0.00±0.00	1.000
Piloerection	0.00±0.00	0.00±0.00	1.000
Startle response	0.96±0.04	1.00±0.00	0.819
Gait	0.00±0.00	0.00±0.00	1.000
Pelvic elevation	2.22±0.08	2.25±0.08	0.866
Tail elevation	1.41±0.10	1.32±0.09	0.589
Touch escape	2.04±0.08	2.07±0.10	0.839
Positional Passivity	1.00±0.00	0.96±0.04	0.825
Above Arena
Abnormal behavior	0.00±0.00	0.00±0.00	1.000
Visual placing	3.00±0.00	3.00±0.00	1.000
Grip strength	2.04±0.10	1.50±0.15	0.006
Body tone	1.00±0.00	1.00±0.00	1.000
Pinna reflex	1.00±0.00	1.00±0.00	1.000
Corneal reflex	1.00±0.00	1.00±0.00	1.000
Toe Pinch	2.52±0.15	2.75±0.13	0.316
Wire manoeuvre	0.11±0.08	0.04±0.04	0.806
Supine Restraint
Skin color	0.96±0.04	0.89±0.06	0.659
Heart rate	1.48±0.10	1.32±0.09	0.311
Limb tone	1.15±0.07	1.11±0.06	0.799
Abdominal tone	1.00±0.00	1.00±0.00	1.000
Lacrimation	0.00±0.00	0.00±0.00	1.000
Salivation	0.37±0.10	0.43±0.11	0.826
Provoked biting	0.67±0.09	0.68±0.09	0.946
Righting reflex	0.00±0.00	0.00±0.00	1.000
Contact righting reflex	1.00±0.00	1.00±0.00	1.000
Negative geotaxis	0.11±0.06	0.32±0.12	0.352
Fear	0.59±0.10	0.54±0.10	0.723
Irritability	0.41±0.10	0.36±0.09	0.755
Aggression	0.59±0.10	0.39±0.09	0.206
Vocalization	0.19±0.08	0.25±0.08	0.685

Unpaired t-test with Bonferroni’s correction, significance is achieved at a p < 0.001.