Table 2 . Adverse effects reported by the patients during treatment .

Adverse effect		OAF-400	OAF-600	p -value
Malaise		0 (0%)	7 (6.7%)	0.007
Nausea & Vomiting		2 (1.9%)	19 (18.1%)	0.04
Bitter taste		0 (0%)	2 (1.9%)	0.15
Dizziness		4 (3.8%)	12 (11.4%)	0.03
Dyspepsia		0 (0%)	3 (2.9%)	0.08
Rash		0 (0%)	1 (0.9%)	0.31
Arthralgia		1 (0.9%)	2 (1.9%)	0.56
Orthostatic hypotension		0 (0%)	8 (7.6%)	0.004
Urticaria		1 (0.9%)	1 (0.9%)	0.1
Pruritus		1 (0.9%)	0 (0%)	0.31
Headache		1 (0.9%)	6 (5.7%)	0.055
Abdominal pain		1 (0.9%)	1 (0.9%)	1
Chest pain		0 (0%)	1 (0.9%)	0.31
Diarrhea		1 (0.9%)	2 (1.9%)	0.56
Bloating		2 (1.9%)	0 (0%)	0.15
Fever		1 (0.9%)	8 (6.7%)	0.01
Anorexia		1 (0.9%)	2 (1.9%)	0.56
Severity of side effects N (%)	Mild	4(3.8%)	34 (31.4%)	0.001
	Moderate	4(3.8%)	14 (13.3%)
	Severe	9 (8.6%)	6 (5.7%)
	Drug interruption due to side effects	4 (3.8%)	3 (2.8%)