Table 2.

Comparison of methods for determining gene frequencies for present/absent data

			Gene frequency estimate from carrier frequency		Direct countinga
Locus	Count	Carrier frequency	Formula a	Formula b	Count	Gene frequency
Present	109	0.4225	0.2401	0.2398	62	0.2403
Absent	243	0.9419	0.7589	0.7570	196	0.7597
Totalb	352	1.3643	0.9989	0.9968	258	1

^aAssuming a molecular method that can distinguish homozygotes from heterozygotes

^b2 n = 258