Table 1.
Pooled analysis demographics (intent-to-treat population)
| Characteristica | Alcaftadine 0.25% (n = 96) | Olopatadine 0.2% (n = 95) | Placebo (n = 93) | All subjects (n = 284) | P value |
|---|---|---|---|---|---|
| Age, years | 0.601* | ||||
| Mean ± SD | 38.7 ± 13.1 | 37.9 ± 14.9 | 36.7 ± 12.6 | 37.8 ± 13.6 | |
| Min–max | 12–70 | 12–74 | 14–68 | 12–74 | |
| Gender, n (%) | 0.488† | ||||
| Male | 33 (34.4) | 33 (34.7) | 39 (41.9) | 105 (37.0) | |
| Female | 63 (65.6) | 62 (65.3) | 54 (58.1) | 179 (63.0) | |
| Ethnicity, n (%) | 1.000† | ||||
| Hispanic or Latino | 9 (9.4) | 9 (9.5) | 9 (9.7) | 27 (9.5) | |
| Not Hispanic or Latino | 87 (90.6) | 86 (90.5) | 84 (90.3) | 257 (90.5) | |
| Race, n (%) | 0.912† | ||||
| African American | 12 (12.5) | 15 (15.8) | 16 (17.2) | 43 (15.1) | |
| Asian | 19 (19.8) | 20 (21.1) | 20 (21.5) | 59 (20.8) | |
| Caucasian | 56 (58.3) | 53 (55.8) | 53 (57.0) | 162 (57.0) | |
| Other | 9 (9.4) | 7 (7.4) | 4 (4.3) | 20 (7.0) | |
| Iris color, n (%) | <0.0001† | ||||
| Brown | 118 (61.5) | 118 (62.1) | 124 (66.7) | 360 (63.4) | |
| Blue | 38 (19.8) | 40 (21.1) | 22 (11.8) | 100 (17.6) | |
| Green | 28 (14.6) | 6 (3.2) | 22 (11.8) | 56 (9.9) | |
| Hazel | 4 (2.1) | 20 (10.5) | 14 (7.5) | 38 (6.7) | |
| Black | 4 (2.1) | 6 (3.2) | 2 (1.1) | 12 (2.1) | |
| Gray | 0 (0.0) | 0 (0.0) | 2 (1.1) | 2 (0.4) |
Max maximum, Min minimum, SD standard deviation
*Analysis of variance, † Fisher’s exact test
aPercentages are based on the total number of subjects in each treatment group except for iris color, which is based on the total number of eyes in each treatment group