Table 2.
Clinical characteristics of the APS positive and negative patients
| Characteristics | n | APS patients (n = 70) | APS negative patients (n = 177) | p value |
|---|---|---|---|---|
| Female/male gender (n) | 160/87 | 44/26 | 116/61 | 0.852 |
| Median age, years (range) | 247 | 37.0 (18–66) | 38.1 (18–65) | 0.478 |
| Type of thrombosis [no. (%)] | ||||
| Proximal deep vein thrombosis | 105 | 21 (30.0) | 84 (47.45) | 0.007 |
| Pulmonary embolism | 44 | 14 (20.0) | 30 (16.95) | 0.762 |
| Cerebral vein thrombosis/stroke | 55 | 11 (15.4) | 44 (24.86) | 0.192 |
| Pregnancy loss | 26 | 10/44 (22.72) | 16/116 (13.79) | 0.151 |
| Distal deep vein thrombosis | 51 | 20 (28.57) | 33 (18.64) | 0.341 |
| Inherited thrombophilia [no. (%)] | ||||
| Antithrombin deficiency | 6 | 4 (5.71) | 2 (1.1) | 0.002 |
| Protein C deficiency | 5 | 2 (2.86) | 3 (1.7) | 0.219 |
| Protein S deficiency | 2 | 1 (1.43) | 1 (0.56) | 0.256 |
| Factor V G1691A | 37 | 12 (17.14) | 25 (14.12) | 0.086 |
| Prothrombin G20210A | 8 | 1 (1.43) | 7 (3.95) | 0.516 |