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. 2014 Jul 20;63(11):1129–1140. doi: 10.1007/s00262-014-1579-y

Table 2.

Frequency of MBL deficiency-associated genotypes and MASP2 A/G heterozygosity

Group C NO BT OC G1-2 OC G3
n 172 (174)a 65 (67)a 107 33 63
MBL deficiency-associated genotypes (LXA/O + O/O) (%) 11.6 6.2 15 30.3b 12.7
MASP2 A/G heterozygotes (%) 8.6 7.5 9.3 24.2c 7.9
LXA/O + O/O (MBL2) and A/G (MASP2) (%) 0.6 0 0.9 12.1d 0

C, control group, including NO, patients with no ovarian pathology and BT, patients with benign ovarian tumours; OC, patients with primary ovarian cancer

aNumbers of samples tested for D120G MASP2 polymorphism

b p = 0.05 (vs OC G3); p = 0.01 (vs C); p = 0.04 (vs NO); p = 0.07 (vs BT)

c p = 0.06 (vs OC G3); p = 0.02 (vs C); p = 0.03 (vs NO); p = 0.04 (vs BT)

d p = 0.01 (vs OC G3); p = 0.002 (vs C); p = 0.01 (vs NO); p = 0.01 (vs BT)