Inhibition of HO1 activity attenuates UTI’s anti-inflammatory and antioxidant activities. Mice in OVA + UTI + ZnPP group were injected with ZnPP (20 mg·kg−1·day−1, i.p.) 1 h before each UTI injection. At 24 h after final OVA challenge, BALF levels of IL-4 (A), IFN-γ (C) and total SOD activity (D), and lung tissue level of MDA (B) were measured. Means ± SD of 10 mice per group. *P < 0.05, compared with control group. #P < 0.05, compared with OVA alone group. $P < 0.05, compared with OVA + UTI group.