Skip to main content
. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Biol Psychiatry. 2014 Apr 25;77(5):475–487. doi: 10.1016/j.biopsych.2014.04.009

Figure 8. Activation of spinal CB2 receptors suppressed paclitaxel-induced allodynia in WT but not CB2KO mice.

Figure 8

Intrathecal administration of AM1710 (5 μg i.t.) suppressed paclitaxel-induced (A, C) mechanical and (B, D) cold allodynia in (A, B) WT, but not (C, D) CB2KO mice. BL, pre-paclitaxel baseline; PTX, post-paclitaxel baseline. Data are expressed as mean ± SEM (n=6 per group). *P<0.05 vs. vehicle, one-way ANOVA followed by Bonferroni post hoc test. #P<0.05 vs. pre-paclitaxel baseline (BL), repeated measures ANOVA.