Table 1.
Lymph node status associated with pathologic features.
| All Cases N |
Node negative N (%) |
Node positive N (%) |
p-value | |
|---|---|---|---|---|
| Tumor Stage | ||||
| T1a (intramucosal) | 72 | 69 (96) | 3 (4) | <0.001 |
| T1b (submucosal) | 138 | 100 (72) | 38 (28) | |
| Depth of Invasion, Intramucosal Only | ||||
| T1a superficial | 35 | 34 (97) | 1 (3) | 1.000 |
| T1a deep | 37 | 35 (95) | 2 (5) | |
| Depth of Invasion, Submucosal Only | ||||
| T1b superficial | 72 | 57 (79) | 15 (21) | 0.049 |
| T1b deep | 66 | 43 (65) | 23 (35) | |
| Lymph Node Stage | ||||
| N0 (0 positive lymph nodes) | 169 | 169 (100) | 0 (0) | N/A |
| N1 (1–2 positive lymph nodes) | 26 | 0 (0) | 26 (100) | |
| N2 (3–6 positive lymph nodes) | 10 | 0 (0) | 10 (100) | |
| N3 (>6 positive lymph nodes) | 5 | 0 (0) | 5 (100) | |
| Lymph nodes examined (median, interquartile range) | 20 (13–28) | 19 (14–28) | 20 (13–28) | 0.969 |
| WHO Tumor Grade | ||||
| Well differentiated | 40 | 38 (95) | 2 (5) | 0.003 |
| Moderately differentiated | 138 | 111 (80) | 27 (20) | |
| Poorly differentiated | 32 | 20 (62) | 12 (38) | |
| Tumor Budding | ||||
| None | 117 | 105 (90) | 12 (10) | <0.001 |
| Focal (1 to 2 budding fields) | 34 | 29 (85) | 5 (15) | |
| Extensive (≥ 3 budding fields) | 59 | 35 (59) | 24 (41) | |
| Tumor Budding | ||||
| None or Focal (< 3 budding fields) | 151 | 134 (89) | 17 (11) | <0.001 |
| Extensive (≥ 3 budding fields) | 59 | 35 (59) | 26 (41) | |
| Angiolymphatic Invasion | ||||
| Absent | 174 | 150 (86) | 24 (14) | <0.001 |
| Present | 36 | 19 (53) | 17 (47) | |
| Tumor Size | ||||
| < 2 cm | 105 | 97 (92) | 8 (8) | <0.001 |
| ≥ 2 cm | 105 | 72 (69) | 33 (31) | |