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. Author manuscript; available in PMC: 2014 Oct 26.
Published in final edited form as: Stat Med. 2014 Jan 29;33(15):2554–2566. doi: 10.1002/sim.6101

Table 1.

Simulation results of fitting the proposed joint model and the reduced model for setting I in which the terminal event is independent on the relapse process subject to misclassification.

Joint Model Reduced Model


Parameter Bias SE SEM CP Bias SE SEM CP
For the probability of IBTR being NP
α0 = −2 −0.082 0.319 0.312 0.952 −0.056 0.316 0.306 0.952
α1 = 3 0.102 0.433 0.419 0.947 0.083 0.427 0.414 0.946
α2 = 4 0.117 0.624 0.608 0.947 0.094 0.624 0.603 0.946
p = 0.8 0.006 0.056 0.055 0.921 0.002 0.056 0.055 0.933
q = 0.9 −0.000 0.020 0.020 0.940 0.000 0.021 0.020 0.939
For the time to IBTR
β1 = 0.5 0.014 0.091 0.091 0.946 0.003 0.088 0.085 0.938
β2 = 0.5 0.012 0.185 0.183 0.950 0.003 0.181 0.175 0.941
ζ = 3 0.108 0.266 0.278 0.953 0.031 0.238 0.233 0.945
For the time to terminal event
η1 = 0.5 0.075 0.128 0.121 0.950 0.004 0.071 0.069 0.944
η2 = 0.5 0.076 0.188 0.190 0.959 0.002 0.139 0.138 0.950
γ = 0 0.079 1.044 1.863 0.998