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. Author manuscript; available in PMC: 2014 Oct 26.
Published in final edited form as: Stat Med. 2014 Jan 29;33(15):2554–2566. doi: 10.1002/sim.6101

Table 2.

Simulation results of fitting the proposed joint model and the reduced model for setting II in which the terminal event is dependent on the relapse process subject to misclassification.

Joint Model Reduced Model


Parameter Bias SE SEM CP Bias SE SEM CP
For the probability of IBTR being NP
α0 = −2 −0.015 0.355 0.338 0.915 0.061 0.345 0.358 0.926
α1 = 3 0.047 0.459 0.461 0.926 −0.097 0.459 0.476 0.915
α2 = 4 0.036 0.644 0.660 0.940 −0.118 0.651 0.688 0.935
p = 0.8 0.009 0.072 0.069 0.916 −0.008 0.073 0.074 0.942
q = 0.9 0.001 0.022 0.022 0.940 0.002 0.022 0.022 0.940
For the time to IBTR
β1 = 0.5 0.003 0.124 0.117 0.946 −0.112 0.099 0.093 0.752
β2 = 0.5 −0.004 0.251 0.235 0.936 −0.105 0.211 0.203 0.903
ζ = 3 0.053 0.378 0.355 0.936 −0.316 0.262 0.262 0.769
For the time to terminal event
η1 = 0.5 0.026 0.139 0.149 0.958 −0.207 0.066 0.065 0.122
η2 = 0.5 0.012 0.261 0.264 0.953 −0.215 0.142 0.135 0.645
γ = 0.5 0.026 0.262 0.262 0.880