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. Author manuscript; available in PMC: 2014 Oct 26.
Published in final edited form as: Stat Med. 2014 Jan 29;33(15):2554–2566. doi: 10.1002/sim.6101

Table 3.

Simulation results of fitting the proposed joint model and the reduced model where data are simulated from the multivariate random effects survival model.

Joint Model Reduced Model


Parameter Bias SE SEM CP Bias SE SEM CP
For the probability of IBTR being NP
α0 = −2 −0.062 0.436 0.389 0.906 0.117 0.411 0.380 0.872
α1 = 3 0.092 0.560 0.514 0.918 −0.115 0.547 0.503 0.875
α2 = 4 0.140 0.794 0.728 0.928 −0.162 0.744 0.719 0.896
p = 0.8 0.008 0.069 0.066 0.908 −0.004 0.070 0.069 0.931
q = 0.9 0.001 0.022 0.022 0.942 0.000 0.023 0.022 0.929
For the time to IBTR
β1 = 0.5 −0.002 0.135 0.122 0.930 −0.122 0.093 0.092 0.721
β2 = 0.5 0.012 0.260 0.241 0.935 −0.118 0.21 0.196 0.883
ζ = 3 −0.005 0.428 0.400 0.917 −0.526 0.26 0.253 0.442
For the time to terminal event
η1 = 0.5 0.010 0.111 0.114 0.954 −0.111 0.071 0.066 0.608
η2 = 0.5 0.015 0.195 0.197 0.960 −0.112 0.134 0.136 0.875