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. 2014 Jul 10;3(7):694–704. doi: 10.1016/j.molmet.2014.07.002

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© 2014 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).

PMC Copyright notice

Response of AgRP DTR animals to restricted feeding during the dark phase. (A, B) Percent body weight and daily food intake of animals on restricted feeding. AgRP DTR animals weight and food consumption was comparable to DTR animals. n ≥ 7 in each group. (C) 24 h plot of activity of DTR and AgRP DTR animals after 3 days on restricted feeding protocol. Error bars were excluded for clarity of plot. (D) Bin plots of activity counts after 3 days on restricted feeding protocol. AgRP DTR exhibited feeding anticipatory activity (FAA) though to a significantly lower extent than DTR animals (DTR 14310 ± 942 vs AgRP DTR 9579 ± 831.1, p < 0.01). n = 4 in each group.