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. 2014 Jul 29;3(7):770–777. doi: 10.1016/j.molmet.2014.07.006

Figure 1.

Figure 1

(A) FoxO1 and Dbh expression in cells of the locus coeruleus (LC), adrenal gland (AG), the dorsal root ganglion (DRG), and superior cervical ganglion (SCG). Ct: Adrenal cortex. Me: Adrenal medulla. (B) Norepinephrine contents in FoxO1fl/fl and FoxO1Dbh−/− adrenal glands. (C) Detection of FoxO1 mutant allele in genomic DNA isolated from tissues from FoxO1fl/fl Dbh-cre (FoxO1Dbh−/−) male mouse. (D) Immunohistochemistry in the locus coeruleus, arcuate neurons, the dorsal root ganglion, the superior cervical ganglion of FoxO1fl/fl and FoxO1Dbh−/− mice using anti-FoxO1 antibody. 3V: Third ventricle. ARC: Arcuate nucleus. (E) Norepinephrine content in the brainstem of 36 week-old FoxO1fl/fl and FoxO1Dbh−/− mice. (F) Ucp1 expression in 36 week-old FoxO1fl/fl and FoxO1Dbh−/− brown fat. (G) Urinary epinephrine elimination of 36 week-old FoxO1fl/fl and FoxO1Dbh−/− mice.