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| Non-mucinous AIS/MIA/LPA | Invasive mucinous adenocarcinoma | |
|---|---|---|
| Cell type | ||
| Mucin-filled | √ | |
| Columnar | √ | |
| Goblet | √ | |
| Type II pneumocyte | √ | |
| Clara cell | √ | |
| IHC | ||
| CK7 | +++ | +++ |
| CK20 | + | ++ |
| TTF-1 | ++ | + |
| Genotype | ||
| KRAS mutation | + | +++ |
| EGFR mutation | ++ | + |
AIS, adenocarcinoma in situ; MIA, minimally invasive adenocarcinoma; LPA, lepidic-predominant adenocarcinoma; EGFR, epidermal growth factor receptor.
