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. 2014 Oct;6(Suppl 5):S537–S546. doi: 10.3978/j.issn.2072-1439.2014.04.05

Table 2. Summary of the Fleischner Society guidelines for the management of subsolid pulmonary nodules (10).

Nodule type Recommendation
Solitary pure GGN <5 mm (assessed with contiguous CT sections of <1 mm)
≤5 mm No follow up
>5 mm Follow up with CT at 3 months, and then yearly monitoring for a minimum of 3 years if persistant and unchanged. (FDG-PET is of limited value and therefore not recommended)
Subsolid GGNs Follow up with CT at 3 months to confirm persistence
<5 mm If persistent and solid measuring <5 mm, then yearly CT monitoring for a minimum of 3 years
≥5 mm If persistent and solid measuring ≥5 mm, then biopsy or surgical resection should be considered. If subsolid nodules measure >10 mm FDG PET should be considered for further evaluation
Multiple subsolid nodules Follow up with CT at 3 months to confirm persistence
Pure GGNs ≤5 mm Follow up CT at 2 and 4 years to monitor. If persistent and solid measuring <5 mm, then yearly CT monitoring for a minimum of 3 years
Pure GGNs >5 mm with no dominant lesion If persistent biopsy or surgical resection should be considered, especially if lesion has a >5 mm solid component
Dominant nodule with subsolid or solid component

GGN, ground glass nodule; CT, computed tomography.