Figure 1. Microfluidics based high-throughput plasmonic biosensing platform using dual-color lensfree on-chip imaging configuration.

(a) Photograph of the on-chip sensing device that employs a plasmonic substrate located at the bottom of a microfluidic channel. Figure Inset: The head of the lensfree device that contains two spectrally different LEDs (with 820 nm and 880 nm peak wavelengths) for simultaneous illumination of the microfluidic chip. (b) Schematics of the on-chip biosensing device composed of a battery, two LEDs, a plasmonic chip, a microfluidic chamber, and a CMOS imager chip. (c) Photograph of the microfluidic system with inlet and outlet ports. (d) Schematic illustration of the flow-over scheme for delivery of target samples to the plasmonic substrate.