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. 2014 Oct 11;4:56. doi: 10.1186/s13550-014-0056-0

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Copyright © 2014 van Oosterom et al.; licensee Springer.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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Imaging results for a mouse with a 4 T1-luc + tumor. Bioluminescence images are obtained by D-Luciferin injection. Fluorescence and SPECT images are obtained by injection of multimodal tracer ¹¹¹In-RGD-MSAP. (A) U-SPECT-BioFluo. Bioluminescent images both with and without median filter applied. (B) IVIS. (C) U-SPECT-BioFluo: 1-mm thick horizontal SPECT slices (anterior to posterior). Organs have been indicated in the SPECT images. White circles indicate the tumor location in the slices.