Table 1.
ET | Controls | |
---|---|---|
N | 20 | 19 |
Age (years) | 83.0 ± 8.3 | 82.5 ± 7.4 |
Female gender | 65% | 47.4% |
Brain weight (g) | 1,209 ± 106 | 1,232 ± 112 |
Postmortem interval (h) | 4.6 ± 3.4 | 7.1 ± 7.8 |
Braak AD stage (median, range)* | 2.0, 0–4 | 1.0, 0–4 |
aCERAD plaque score (median, range) | 0, 0–3 | 0, 0–1 |
bPC count* | 31.8 ± 6.4 | 46.0 ± 12.6 |
bAxonal torpedoes* | 13.3 ± 13.9 | 2.7 ± 2.9 |
Parallel fiber integrated density | 23798.2 ± 16789.7 | 33515.1 ± 36261.0 |
Parallel fiber count | 11.3 ± 4.2 | 10.3 ± 4.1 |
Mean ± standard deviation and frequency (%) are reported unless otherwise specified
p < 0.01, cases versus controls. Student’s t test was used for comparisons of means, Mann–Whitney test was used for comparison of medians, and χ2 tests were used for comparison of proportions
CERAD plaque scores were converted from letters to numbers: 0, absent; 1, sparse; 2, moderate; and 3, severe
In each brain, torpedoes in the entire 3 × 20 × 25 mm section were counted, and PCs in five 100× fields were counted and averaged