Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pro- and anti-tumorigenic roles of osteonectin in pancreatic cancer development and progression. Osteonectin (ON) is a multifaceted protein with controversial functions of its structural domains. ON is anti-tumorigenic and inhibits proliferation, migration, colony and xenograft formation as well as invasiveness. Facilitation of pericyte migration by ON contributes to inhibition of tumor spread. However, ON is also pro-tumorigenic and induces invasiveness.
