Table 3.
Comparison of survivors and non-survivors at 28 d
| Characteristics |
28-d mortality |
||
| Yes (n = 19) | No (n = 31) | P value | |
| Age (yr) | 45 ± 121 | 47 ± 14 | 0.649 |
| Male gender | 16 (84)2 | 27 (87) | 1.000 |
| Prior decompensation | 11 (57.9) | 17 (54.8) | 0.833 |
| Bilirubin (mg/dL) | 17.7 (1.2-37.6)3 | 10.7 (0.6-43.0) | 0.139 |
| Total leukocyte count (/mm3) | 11200 (2700-39000) | 9300 (3600-36400) | 0.873 |
| Platelet count (103/mm3) | 81.0 (14.8-382.0) | 90.0 (14.4-444.0) | 0.734 |
| International normalized ratio | 2.7 ± 0.7 | 2.3 ± 0.8 | 0.054 |
| Serum creatinine (mg/dL) | 2.2 (0.5-7.9) | 1.6 (0.6-6.3) | 0.509 |
| Jaundice | 18 (95) | 27 (87) | 0.637 |
| Ascites | 17 (90) | 25 (81) | 0.693 |
| Hepatic encephalopathy | 10 (53) | 7 (23) | 0.037 |
| Upper gastrointestinal bleed | 1 (5) | 5 (16) | 0.387 |
| Organ failures | |||
| Liver | 14 (74) | 15 (48) | 0.139 |
| Kidney | 12 (63) | 10 (32) | 0.033 |
| Cerebral | 5 (26) | 0 (0) | 0.005 |
| Coagulation | 12 (63) | 11 (36) | 0.057 |
| Respiratory | 0 (0) | 2 (11) | 0.140 |
| Circulation | 1 (5) | 1 (5) | 1.000 |
| Prognostic scores | |||
| Child-Pugh score | 12.3 ± 1.3 | 10.8 ± 1.7 | 0.002 |
| MELD score | 32.8 ± 7.1 | 27.1 ± 7.5 | 0.010 |
| APACHE II score | 15.0 (8-41) | 10.0 (4.0-25.0) | 0.001 |
| CLIF-SOFA score | 11.6 ± 2.5 | 8.8 ± 2.3 | < 0.001 |
1
mean ± SD;
2
Number (percentage);
3
Median (range). ACLF: Acute-on-Chronic Liver Failure; APACHE: Acute Physiology and Chronic Health Evaluation; APASL: Asia-Pacific Association for the Study of Liver; CLIF-SOFA: Chronic Liver Failure-Sequential Organ Failure Assessment; MELD: Model for End-stage Liver Disease.