Table 3.
BRCA1 Gene Mutations identified in the breast cancer patients from Kerman Province, Iran
| Mutation | Nt | Coding | Amino acid | % | N | Reference |
| TGT>AGT | 939 | c.822 | p.Cys274 Ser | 3.3 | 1 | – |
| ACT>ACA | 1118 | c.999 | p.Thr333Thr | 6.7 | 2 | – |
| CAG>CGG | 1186 | c.1068 | p.Gln356Arg | 3.3 | 1 | BIC:17667 |
| AAG>A-G | 1135 | c.1017 | p.Lys340Stop | 10 | 3 | BIC: 1160 |
| GCT>GCC | 1085 | c. 966 | p.Ala322Ala | 3.3 | 1 | – |
| GGA>GGT | 1088 | c.969 | p.Gly323Gly | 3.3 | 1 | – |
| GGG>CGG | 942 | c. 825 | p.Gly275Arg | 3.3 | 1 | – |
| INS C | 1088 | c. 969 | p.Gly323Stop | 10 | 3 | – |
| AGT>CGT | 909 | c.792 | p.Ser264Arg | 3.3 | 1 | – |
| Unknown | – | – | – | 53.5 | 16 | – |
| Total | – | – | – | 100 | 30 | – |
N; Number, %; Percent, Nt; Nucleotide