Table 5. The prevalence of diseases or diseases worsened by nanomaterials handling work stratified by risk levels.

Variables	Prevalence										Worsened by work
	Control (n=200)			Risk Level 1 (n=139)			Risk Level 2 (n=119)		p-value*		Control (n=200)			Risk Level 1 (n=139)			Risk Level 2 (n=119)		p-value*
	N	(%)		N	(%)		N	(%)			N	(%)		N	(%)		N	(%)
Respiratory Diseases
Chronic Bronchitis	11	5.5%		8	5.8%		6	5.0%	0.96		0	0.0%		3	2.2%		2	1.7%	0.13
Emphysema	0	0.0%		0	0.0%		0	0.0%	.		0	0.0%		0	0.0%		0	0.0%	.
Asthma	7	3.5%		4	2.9%		2	1.7%	0.63		0	0.0%		1	0.7%		1	0.8%	0.46
Tuberculosis	1	0.5%		0	0.0%		0	0.0%	0.52		0	0.0%		0	0.0%		0	0.0%	.
Lung cancer	1	0.5%		0	0.0%		0	0.0%	0.52		0	0.0%		0	0.0%		0	0.0%	.
Rhinitis	37	18.7%		27	19.4%		23	19.3%	0.98		1	0.5%		5	3.6%		2	1.7%	0.10
Cardiovascular diseases
Stroke	0	0.0%		0	0.0%		0	0.0%	.		0	0.0%		0	0.0%		0	0.0%	.
Arrhythmia	2	1.0%		5	3.6%		7	5.9%	0.05		0	0.0%		0	0.0%		1	0.8%	0.24
Ischemic heart dis	0	0.0%		0	0.0%		1	0.8%	0.24		0	0.0%		0	0.0%		0	0.0%	.
Angina	0	0.0%		0	0.0%		5	4.2%	<0.01		0	0.0%		0	0.0%		0	0.0%	.
Valve heart dis.	3	1.5%		2	1.4%		2	1.7%	0.99		0	0.0%		0	0.0%		0	0.0%	.
Hyperlipidemia	13	6.6%		9	6.5%		11	9.2%	0.62		1	0.5%		1	0.7%		1	0.8%	0.93
Hypertension	12	6.1%		9	6.5%		11	9.2%	0.54		2	1.0%		2	1.4%		0	0.0%	0.45
Skin Diseases
Atopic dermatitis	9	4.5%		11	7.9%		9	7.6%	0.37		0	0.0%		1	0.7%		1	0.8%	0.46
Allergic dermatitis	19	9.6%		8	5.8%		18	15.1%	0.04		1	0.5%		0	0.0%		5	4.2%	0.01
Pigmentation	3	1.5%		2	1.4%		5	4.2%	0.22		0	0.0%		0	0.0%		0	0.0%	.
Skin cancer	0	0.0%		2	1.4%		1	0.8%	0.26		0	0.0%		0	0.0%		0	0.0%	.
Folliculitis	9	4.5%		7	5.0%		7	5.9%	0.87		0	0.0%		0	0.0%		1	0.8%	0.24

*χ²p-value