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. 2014 Sep;5(9-10):353–364. doi: 10.18632/genesandcancer.33

Table 2. Analysis of miR-155 Regulated Pathways.

Up Regulated Pathways Down Regulated Pathways miR-155 Targeted Pathways
MAPK Signaling Pathway Rho cell motility signaling pathway Rac1 cell motility signaling pathway
RHO cell motility signaling pathway Rac1 cell motility signaling pathway Regulation of bad phosphorylation
Integrin signaling pathway Ras signaling pathway Bioactive peptide induced signaling pathway
Rac1 Cell Motility Signaling Pathway Integrin signaling pathway Transcription factor creb and its extracellular signals
Inhibition of Cellular Proliferation by Gleevec Role of Brca1 Brca2 and Atr in cancer susceptibility Growth hormone signaling pathway
ERK and PI3K collagen in corneal epithelia Proteasome complex Rho cell motility signaling pathway
Negative effectors of Fas and TNF Hiv-1 nef: negative effector of fas and tnf Cell cycle: g1/s check point
Bioactive peptide induced signaling pathway Cyclin E destruction pathway Co-stimulatory signal during t-cell activation
P38 MAPK signaling pathway Ifn alpha signaling pathway Igf-1 signaling pathway
Induction of apoptosis through DR3 and DR4/5 death receptors Map kinase signaling pathway Ras signaling pathway
Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells ERK and PI3 kinase are necessary for collagen binding in corneal epithelia Phospholipase c signaling pathway
Ras signaling pathway Hypoxia and p53 in the cardiovascular system ATM Hiv-1 nef: negative effector of fas and tnf
Control of skeletal myogenesis by HDAC and calcium/calmodulin dependent kinase (CAMK) Caspase cascade in apoptosis Human cytomegalovirus and map kinase pathways
Growth hormone signaling pathway Rb tumor suppressor/checkpoint signaling in response to dna damage Akt signaling pathway
ERK1/ERK2 MAPK signaling pathway D4GDI signaling pathway Egf signaling pathway
IL-7 signal transduction Cell cycle: g1/s check point ATM Multiple antiapoptotic pathways from igf-1r signaling lead to bad phosphorylation
FC epsilon receptor I signaling in mast cells Links between pyk2 and map kinases Trka receptor signaling pathway
IL-22 soluble receptor signaling pathway Transcription factor creb and its extracellular signals Map kinase signaling pathway
Apoptotic DNA-fragmentation and tissue homeostasis CDC25 and chk1 regulatory pathway in response to dna damage Role of pi3k subunit p85 in regulation of actin organization and cell