Table 3.
Internalizing antibodies to specific cell surface proteins isolated by selection on cells.
| Cell surface protein | Antibody | Activity | Reference |
|---|---|---|---|
| HER2 | F5 | Targeted Liposomal drug | [33] |
| Transferrin receptor | H7, PR5 | [33], [34] | |
| EGFR | C10 and affinity F4 | [32], [54] | |
| CD146 | M1 | Targeted Liposomal drug | [39] [49] |
| CD166 | I/F8 H3 |
Immunotoxin Targeted Liposomal drug |
[51] [35], [52] |
| ICAM-1 | M10A12 | Block cell invasion | [35], [50] |
| FLT3 | EB10, A2IN, D4-3 | Suppress cell growth | [53] |
| Integrein α3β1 | SW1, PAN10 | SW1 mimic ligand | [34] |
| EphA2 | D2-1A7, D2-1A9 | [36] | |
| CD44 | F2-1A6, F2-1H9 | [36] |