Skip to main content
. Author manuscript; available in PMC: 2015 Sep 24.
Published in final edited form as: JAMA. 2014 Sep 24;312(12):1237–1247. doi: 10.1001/jama.2014.10059

Figure 1. Study flow diagram.

Figure 1

Flow diagram derived from Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). This diagram reports results of search through October 1 2013; a follow-up search through June 13 2014 revealed a publication reporting updated data from one of the publications identified here, so the updated data were used in our analysis.

* Of the 10 ‘patient only’ and 29 ‘integrated’ studies, 2 studies had one trial arm that fell into both categories, resulting in 37 studies in total.