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TMtb-iNet preserved more genes overlapped with those in the active PTB signature. Of the 55 genes overlapped between the THP1r2Mtb-induced and active PTB signatures, 36 were still present in TMtb-iNet, whereas only 19 were in TMtb-iEx. This biased distribution is statistically significant (P = 1.13 × 10−3, Fisher's exact test).
