Table 2.
Correlation analysis between clinical and cytometry bead array data (geometric mean of the released cytokines) using unadjusted as well as adjusted estimation procedures (significant differences are shown in bold).
| IFNγ | IL-17 | IL-10 | CXCL8 | IL-6 | IL-13 | IP-10 | IL-1 | RANTES | |
|---|---|---|---|---|---|---|---|---|---|
| Age | |||||||||
| Unadjusted correlation | −0.27 (P = 0.14) | −0.36 (P = 0.05) | −0.30 (P = 0.11) | 0.64 ( P < 0.001) | 0.26 (P = 0.16) | −0.003 (P = 0.99) | 0.30 (P = 0.11) | −0.24 (P = 0.20) | −0.27 (P = 0.15) |
| Adjusted correlation | −0.35 ( P = 0.02) | −0.22 (P = 0.12) | −0.34 ( P = 0.04) | 0.52 ( P = 0.001) | 0.21 (P = 0.23) | −0.08 (P = 0.58) | 0.28 (P = 0.10) | −0.21 (P = 0.18) | −0.28 (P = 0.09) |
| Gender | |||||||||
| Unadjusted correlation | 0.01 (P = 0.95) | −0.10 (P = 0.60) | −0.06 (P = 0.75) | −0.02 (P = 0.92) | 0.08 (P = 0.69) | 0.12 (P = 0.54) | 0.01 (P = 0.95) | −0.08 (P = 0.66) | 0.08 (P = 0.66) |
| Adjusted correlation | 0.03 (P = 0.82) | 0.06 (P = 0.65) | −0.01 (P = 0.93) | −0.15 (P = 0.30) | −0.11 (P = 0.51) | 0.10 (P = 0.50) | −0.04 (P = 0.83) | −0.11 (P = 0.49) | 0.03 (P = 0.88) |
| Total tear volume | |||||||||
| Unadjusted correlation | −0.25 (P = 0.19) | −0.26 (P = 0.16) | −0.12 (P = 0.53) | −0.36 (P = 0.05) | 0.03 (P = 0.88) | −0.60 ( P < 0.001) | −0.52 ( P = 0.004) | −0.09 (P = 0.63) | −0.19 (P = 0.32) |
| Adjusted correlation | −0.17 (P = 0.25) | −0.22 (P = 0.12) | −0.08 (P = 0.64) | −0.37 ( P = 0.02) | −0.09 (P = 0.61) | −0.31 ( P = 0.04) | −0.32 (P = 0.06) | 0.06 (P = 0.68) | −0.12 (P = 0.45) |