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. 2014 Jul 15;44(9):2692–2702. doi: 10.1002/eji.201344245

Figure 1.

Figure 1

WAS KO mice develop exacerbated experimental arthritis. (A) H&E stainings of knee joints for cellular infiltrates in C57BL/6 and WAS KO mice, indicated by asterisks. Representative images are shown from day 7; cart: articular cartilage; ep: epiphyseal plate; fp: fat pad; lig: ligament. Scale bar 500 μm. (B, C) Severity of arthritis was assessed as (B) a clinical walking score and (C) knee swelling. Data are shown as mean ± SEM of nine animals per group up to day 4, and four animals per group at day 7; data are from a single experiment. *p < 0.05, **p < 0.01, ***p < 0.001, unpaired Student's t-test.