| Dimension | MSPT Test | MSFC Test | Comment |
| Lower extremity function | WST | 25FW | WST has been shown to correlate with EDSS, and patient self-reports |
| Walking and standing stability | Balance Test | None | Imbalance is a common MS manifestation, but there are no practical balance tests for general use |
| Hand coordination | MDT | 9HPT | 9HPT has been shown to be informative in clinical trials |
| Cognitive processing speed | PST | SDMT | PASAT-3 was recommended for the initial version of the MSFC, but an expert panel has recommended that it be replace by SDMT |
| Vision | LCLAT | SLCLA | SLCLA has been validated in MS patients and recommended for future versions of the MSFC |
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