Table 1.

The human OATPs with each signature sequence region. OATP1B1 amino acids mutated during this study are bold and underlined. Source: NCBI [18].

OATP	Signature sequence
OATP1A2	D	T	R	W	V	G	A	W	W	F	G	F	L
OATP1B1	D	S	R	W	V	G	A	W	W	L	N	F	L
OATP1B3	D	S	R	W	V	G	A	W	W	L	G	F	L
OATP1C1	D	P	Q	W	V	G	A	W	W	L	G	Y	L
OATP2A1	D	P	R	W	I	G	A	W	W	L	G	L	L
OATP2B1	D	P	R	W	V	G	A	W	W	L	G	F	L
OATP3A1	D	P	R	W	I	G	A	W	W	G	G	F	L
OATP4A1	S	P	L	W	V	G	A	W	W	V	G	F	L
OATP4C1	D	P	R	W	L	G	A	W	W	I	G	F	L
OATP5A1	D	P	R	F	I	G	N	W	W	S	G	F	L
OATP6A1	S	P	E	W	L	W	T	W	W	I	N	F	L