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. Author manuscript; available in PMC: 2014 Oct 27.
Published in final edited form as: Arch Surg. 2012 Apr;147(4):345–351. doi: 10.1001/archsurg.2012.12

Table 3.

Risk Factors for a CAE Between Hospitals That Did and Did Not Routinely Perform an Anastomotic Leak Test After Ileorectal or Colorectal Anastomoses

Routine Anastomotic Leak Test No Routine Anastomotic Leak Test


Characteristic Unadjusted OR of CAE
(95% CI)
Adjusted OR of CAE
(95% CI)
Unadjusted OR of CAE
(95% CI)
Adjusted OR of CAE
(95% CI)
Leak test performed 0.50 (0.17–1.47) 0.23 (0.05–0.99) 1.44 (0.88–2.38) 2.68 (1.14–6.26)
Age, y 1.0 (0.99–1.02) 1.01 (0.98–1.04) 1.01 (1.00–1.02) 1.02 (0.99–1.04)
Male sex 1.97 (1.22–3.20) 3.38 (1.56–7.36) 1.49 (1.01–2.20) 0.97 (0.51–1.84)
Smoker 1.76 (1.03–2.99) 2.01 (0.94–4.33) 1.07 (0.65–1.77) 1.3 (0.58–2.91)
BMI >30 0.76 (0.45–1.31) 0.64 (0.27–1.52) 1.08 (0.70–1.66) 1.23 (0.61–2.47)
Albumin level <3 g/dL 3.24 (1.52–6.90) 4.34 (1.81–10.41) 1.89 (0.95–3.76) 2.16 (0.95–4.90)
Diabetes mellitus 1.15 (0.58–2.29) 0.98 (0.29–3.33) 1.58 (0.94–2.63) 0.8 (0.28–2.27)
Charlson comorbidity index
  1 1.35 (0.77–2.34) 1.42 (0.51–3.93) 1.45 (0.14–15.35) 1.94 (0.84–4.46)
  2 0.89 (0.26–2.99) 1.59 (0.31–8.19) 1.27 (0.51–3.18) 1.16 (0.28–4.88)
  ≥3 5.68 (1.46–22.17) 8.49 (1.43–50.41) 3.34 (1.06–10.50) 1.45 (0.14–15.35)
Immunosuppressed 2.45 (0.91–6.56) 2.39 (0.51–11.12) 3.03 (1.63–5.67) 3.69 (1.44–9.42)
Type of operation 1.08 (0.74–1.57) 1.55 (1.01–2.37) 1.06 (0.82–1.37) 1.04 (0.69–1.59)
Laparoscopic approach 0.42 (0.23–0.79) 0.46 (0.16–1.28) 1.01 (0.65–1.57) 1.25 (0.60–2.63)
Operative time 1.14 (0.98–1.31) 1.0 (0.99–1.00) 1.19 (1.08–1.32) 1.0 (1.00–1.01)
Year of operation 0.84 (0.65–1.08) 0.9 (0.51–1.57) 0.94 (0.81–1.10) 0.87 (0.59–1.27)

Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CAE, composite adverse event; OR, odds ratio.

SI conversion factor: To convert albumin to grams per liter, multiply by 10.