Table 2. Test of Association with Fibrinogen-Positive Area Fraction and Cellular Labelling Score for Deep Grey Matter and Deep Subcortical White Matter.
AF, τ | AF, p | CELL, τ | CELL, p | |
---|---|---|---|---|
Deep grey matter | ||||
Age at death | −0.037 | 0.65 | −0.037 | 0.69 |
History of hypertension | 0.19 | 0.047* | 0.27 | 0.013 * |
Subgroup (SVD or AC) | −0.11 | 0.25 | 0.045 | 0.68 |
SVD severity score1 | −0.038 | 0.66 | 0.088 | 0.36 |
CAA severity2 | −0.031 | 0.73 | 0.003 | 0.98 |
History of dementia | −0.07 | 0.48 | 0.005 | 0.90 |
Postmortem interval | 0.121 | 0.13 | 0.022 | 0.81 |
AF | -- | -- | 0.52 | <0.001** |
Deep white matter | ||||
Age at death | 0.001 | 0.92 | −0.04 | 0.70 |
History of hypertension | −0.03 | 0.78 | −0.062 | 0.61 |
Subgroup (SVD or AC) | −0.072 | 0.53 | −0.043 | 0.72 |
SVD severity score1 | 0.002 | 0.99 | 0.026 | 0.82 |
Leukoaraiosis severity3 | −0.02 | 0.89 | −0.002 | 0.99 |
CAA severity2 | 0.16 | 0.14 | 0.24 | 0.036 * |
History of dementia | 0.25 | 0.043* | 0.055 | 0.69 |
Postmortem interval | −0.015 | 0.88 | 0.09 | 0.39 |
AF | -- | -- | 0.50 | <0.001** |
The table lists Kendall’s tau-b rank correlation coefficient (τ) as a measure of association, and the level of significance (p).
p < 0.05;
p < 0.001.
AF, fibrinogen-positive area fraction; CAA, cerebral amyloid angiopathyi; CELL, cellular labelling score for deep grey matter (caudate-putamen) and for deep subcortical white matter; SVD, small vessel disease.
See (39).
See (44).
See (40).