Table 2.
Recurrent gene lesions
| Cytoband | Start (Mb) | End (Mb) | Size (Mb) | Ependymoma (n = 4) |
Ewing’s sarcoma (n = 9) |
Glioblastoma (n = 7) |
Leukemia (n = 16) |
Lymphoma (n = 3) |
Medulloblastoma (n = 4) |
Neuroblastoma (n = 14) |
Osteosarcoma (n = 7) |
Rhabdoid (n = 6) |
Rhabdomyosarcoma (n = 12) |
Wilms’ tumor (n = 4) |
Total (n = 86) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Amplifications | |||||||||||||||
| 1q21.3-q44 | 150.034 | 245.12 | 95.086 | 3 | 1 | 1 | 0 | 1 | 0 | 10 | 3 | 2 | 6 | 3 | 30 |
| 2p25.1 | 10.062 | 11.645 | 1.583 | 1 | 0 | 0 | 2 | 1 | 0 | 8 | 1 | 0 | 7 | 1 | 21 |
| 2p24.3 | 15.72 | 16.465 | 0.745 | 1 | 0 | 0 | 0 | 0 | 0 | 13 | 1 | 0 | 7 | 1 | 23 |
| 2p24.2-p16.1 | 16.873 | 60.356 | 43.483 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 2 | 0 | 7 | 1 | 16 |
| 2p14 | 64.333 | 65.547 | 1.214 | 0 | 1 | 1 | 2 | 3 | 0 | 2 | 1 | 0 | 5 | 1 | 16 |
| 3q27.2-q27.3 | 18.696 | 18.818 | 0.122 | 0 | 1 | 1 | 1 | 3 | 0 | 2 | 0 | 0 | 1 | 1 | 10 |
| 7p21.1-p11.2 | 13.986 | 54.398 | 40.412 | 1 | 2 | 4 | 1 | 2 | 1 | 8 | 5 | 0 | 4 | 1 | 29 |
| 7q31.31-q35 | 117.011 | 147.281 | 30.27 | 1 | 1 | 4 | 2 | 1 | 1 | 4 | 2 | 0 | 2 | 3 | 21 |
| 8q11.21-q22.3 | 48.151 | 106.195 | 58.044 | 0 | 6 | 3 | 2 | 1 | 1 | 1 | 3 | 0 | 1 | 1 | 19 |
| 8q24.11-q24.21 | 117.746 | 128.809 | 11.063 | 1 | 7 | 3 | 4 | 0 | 1 | 2 | 3 | 0 | 3 | 0 | 24 |
| 9p22.3-p22.2 | 14.438 | 17.312 | 2.874 | 0 | 0 | 4 | 0 | 0 | 1 | 2 | 1 | 0 | 2 | 1 | 11 |
| 12p13.33-p12.1 | 10.76 | 26.234 | 15.474 | 0 | 1 | 2 | 0 | 0 | 0 | 6 | 3 | 0 | 4 | 3 | 19 |
| 12q14.1-q15 | 56.263 | 69.037 | 12.774 | 0 | 2 | 1 | 0 | 0 | 0 | 4 | 1 | 0 | 5 | 3 | 16 |
| 13q14.11 | 39.703 | 40.042 | 0.339 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 2 | 10 |
| 14q11.2 | 21.703 | 22.061 | 0.358 | 1 | 2 | 3 | 3 | 1 | 2 | 3 | 6 | 1 | 3 | 3 | 28 |
| 15q22.31-q23 | 64.63 | 66.673 | 2.043 | 0 | 0 | 4 | 1 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 8 |
| 17q21.31-q25.3 | 41.159 | 78.182 | 37.023 | 0 | 6 | 4 | 3 | 2 | 0 | 13 | 3 | 1 | 3 | 1 | 36 |
| 20p12.2-p12.1 | 9.002 | 17.491 | 8.489 | 0 | 0 | 3 | 1 | 0 | 1 | 0 | 2 | 0 | 2 | 3 | 12 |
| 20q11.23-q13.33 | 33.909 | 62.377 | 28.468 | 0 | 2 | 1 | 2 | 1 | 1 | 2 | 4 | 0 | 7 | 3 | 23 |
| 21q22.3 | 45.112 | 46.015 | 0.903 | 0 | 2 | 0 | 3 | 3 | 0 | 1 | 5 | 0 | 1 | 1 | 16 |
| 22q11.21 | 17.722 | 17.723 | 0.001 | 0 | 2 | 5 | 2 | 0 | 0 | 2 | 3 | 0 | 1 | 0 | 15 |
| Deletions | |||||||||||||||
| 1p36.32-p36.11 | 3.118 | 5.001 | 1.883 | 0 | 2 | 0 | 0 | 0 | 0 | 11 | 0 | 0 | 1 | 1 | 15 |
| 6q22.31-q22.33 | 121.263 | 130.387 | 9.124 | 1 | 0 | 0 | 0 | 3 | 0 | 2 | 2 | 0 | 1 | 0 | 9 |
| 9p21.3 | 21.675 | 22.538 | 0.863 | 1 | 5 | 5 | 11 | 1 | 0 | 1 | 3 | 0 | 2 | 1 | 30 |
| 14q11.2 | 21.942 | 22.033 | 0.091 | 0 | 0 | 0 | 8 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 10 |
| 16q22.3 | 72.413 | 73.507 | 1.094 | 2 | 5 | 2 | 1 | 0 | 0 | 0 | 1 | 0 | 4 | 0 | 15 |